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Supercritical fluid extraction device is composed by the four units, two of the same first three modules can be generic, are from the air tank, refrigerator, pressure pump and extractor component. In the experimental device designed study the repid expansion of supercritical fluid solution process of the operating variables on the prepared particle size of griseofulvin.RESS fine particles prepared mainly by using the solubility of the solute and supercritical fluid density relationship, as from the rapid expansion of supercritical fluid state to a low pressure, low temperature gas state, a sharp decline in the solubility of the trigger sprayer solute, the change to the rapid nucleation and Solute grow into particles and deposition . First, low temperature (room temperature or slightly higher), especially for heat-sensitive biological materials, or drug preparation materials, ultrafine; Second, both the dual characteristics of liquids and gases, diffusion coefficient, viscosity, permeability to obtain high purity products, small and uniform particle size.Preparation of Fine Particles RESS device consists of four modules: freezing unit, pump unit, dissolve unit and collection unit. Fine particles in the current high-tech has become a hot area, the materials, chemicals, light industry, metallurgy, electronics, bio-medicine is widely used. The rapid expansion of supercritical solution obtained the α-asarone of fine particles.

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